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Executive OrderCurrent administrationForeign Affairs & National SecurityImmigrationBudget & TaxesJustice & Public Safety
Designating Fentanyl as a Weapon of Mass Destruction
Donald Trump · 47th PresidentPublished Dec 18, 2025Signed Dec 15, 2025
Document overview
Summary
Section 1 . Purpose and Policy. Illicit fentanyl is closer to a chemical weapon than a narcotic. Two milligrams, an almost undetectable trace amount equivalent to 10 to 15 grains of table salt, constitutes a lethal dose. Hundreds of thousands of Americans have died from fentanyl overdoses. The manufacture and distribution of fentanyl, primarily performed by organized criminal networks, threatens our national security and fuels lawlessness in our hemisphere and at our borders.…
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